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Bladder Cancer
Avelumab as Maintenance Prolongs Survival in Advanced Bladder Cancer
By
Patricia Stewart
Bladder Cancer
August 2020, Vol 10, No 8
Interim analysis of the phase 3 JAVELIN Bladder 100 clinical trial showed that maintenance therapy with the PD-L1 inhibitor avelumab (Bavencio) plus best supportive care significantly prolonged overall survival (OS) versus best supportive care alone in patients with advanced urothelial carcinoma whose disease did not progress with first-line platinum-based chemotherapy.
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Adjuvant Atezolizumab Does Not Show Disease-Free Survival Benefit in High-Risk Bladder Cancer
By
Patricia Stewart
Bladder Cancer
August 2020, Vol 10, No 8
Adjuvant therapy with atezolizumab (Tecentriq) did not meet the primary end point of disease-free survival (DFS) in patients with muscle-invasive urothelial cancer (MIUC) at high risk for recurrence versus observation alone in the primary analysis of the IMvigor010 trial.
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Nivolumab-Based Chemotherapy Regimen Shows Activity in Muscle-Invasive Urothelial Cancer
By
Phoebe Starr
Bladder Cancer
June 2020, Vol 10, No 6
A combination of nivolumab (Opdivo), gemcitabine (Gemzar), and cisplatin as neoadjuvant therapy resulted in a pathologic nonmuscle-invasive rate of 66% and a pathologic complete response rate (pCR) of 49% in patients with muscle-invasive bladder cancer (MIBC), according to results from the phase 2 BLASST-1 clinical trial.
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FDA Grants Priority Review to Keytruda for Patients with High-Risk, Non–Muscle-Invasive Bladder Cancer
By
Yvette Florio Lane
Bladder Cancer
,
FDA Approvals, News & Updates
,
Immunotherapy
Web Exclusives
On December 2, 2019, Merck announced that the FDA has granted priority review for its supplemental biologics license application for the anti–PD-1 agent pembrolizumab (Keytruda). If approved, the drug would be indicated as monotherapy to treat patients with Bacillus Calmette-Guerin–unresponsive, high-risk, non–muscle-invasive bladder cancer who are ineligible for or have decided not to undergo cystectomy.
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Home
Issues
Latest Issue
Issue Archive
Special Issues
2022 Midyear Review: Non–Small-Cell Lung Cancer
2022 Oncology Biosimilar Guide to Patient Support Services
2022 Breast Cancer Guide to Patient Support Services
Browse By Topic
Practice Management
Financial Management
Reimbursement
Health Policy
Quality Care
ICD Codes
Survivorship
FDA Approvals, News & Updates
In the News
Guide to Patient Support Services
Index
Introduction
2023 Spotlight
Conference Correspondent
ASCO 2022 - Wrap Up
NSCLC IO 2022 - Midyear Review
SABCS 2021 Wrap-Up
Dual IO 2021 Year in Review
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